北京索萊寶科技有限公司
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專注于生物學(xué)試劑及試劑盒領(lǐng)域
服務(wù)熱線：18101056239
產(chǎn)品型號：K200021M
更新時(shí)間：2022-08-15
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相關(guān)文章
| 英文名稱 | Anti-NSE Monoclonal Antibody |
|---|---|
| 宿主 | Mouse |
| 別名 | Enolase 2;Neuron specific gamma enolase;ENOG;Eno 2 |
| 應(yīng)用 | WB |
| 稀釋比例 | WB 1:1000-3000. |
| 交叉反應(yīng) | Human Mouse Rat |
| 蛋白分子量 | 47kDa |
| Gene ID | 2026 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 儲存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 純化方法 | Affinity purification |
| 亞型 | IgG1 |
| 免疫原 | A synthetic peptide coupled to KLH |
| 性狀 | 液體 |
| Public Immunogen Range | A synthetic peptide coupled to KLH |
| Subcellular Locations | Cytoplasm Cell membrane |
| Swiss Prot | P09104 |
| 克隆號 | 1.30E+03 |
| 克隆類型 | Monoclonal Antibody |
| 背景資料 | Enolase is a glycolytic enzyme catalyzing the reaction pathway between 2 phospho glycerate and phosphoenol pyruvate. In mammals, enolase molecules are dimers composed of three distinct subunits (alpha, beta and gamma). The alpha subunit is expressed in most tissues and the beta subunit only in muscle. The gamma subunit is expressed primarily in neurons, in normal and in neoplastic neuroendocrine cells. NSE (neuron specific enolase) is found in elevated concentrations in plasma in certain neoplasias. These include pediatric neuroblastoma and small cell lung cancer. Coexpression of NSE and chromogranin A is common in neuroendocrine neoplasms. |
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